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Warning: Cannot modify header information - headers already sent by (output started at /home/u216253868/domains/landonburress.com/public_html/blog/wire/core/Selectors.php:275) in /home/u216253868/domains/landonburress.com/public_html/blog/wire/modules/Process/ProcessPageView.module on line 142
Deprecated: Constant FILTER_SANITIZE_STRING is deprecated in /home/u216253868/domains/landonburress.com/public_html/blog/wire/core/Sanitizer.php on line 293
Deprecated: Constant FILTER_SANITIZE_STRING is deprecated in /home/u216253868/domains/landonburress.com/public_html/blog/wire/core/Sanitizer.php on line 293
Deprecated: Constant FILTER_SANITIZE_STRING is deprecated in /home/u216253868/domains/landonburress.com/public_html/blog/wire/core/Sanitizer.php on line 293 Notes and stuff
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Define membrane potential (Vm) and sodium equilibrium potential (Ena). Which of these, if any, changes during the course of an action potential?
Membrane potential (Vm) is the voltage across the neuronal membrane at any moment. Sodium equilibrium potential (Ena) is the electrical potential difference that exactly balances the sodium concentration gradient. The membrane potential changes during an action potential.
What ions carry the early inward and late outward currents during the action potential?
Na+ ions rush into the cell in the rising phase and K+ ions rush out in the falling phase.
Why is the action potential referred to as "all-or-none"?
Action potentials don't occur unless a threshold is crossed.
Some voltage-gated K+ channels are known as delayed rectifiers because of the timing of their opening during an action potential. What would happen if these channels took much longer than normal to open?
It would delay the neuron's return to the resting membrane potential and any further action potentials.
Imagine we have labeled tetrodotoxin (TTX) so that it can be seen with a microscope. If we wash this TTX on to a neuron, what parts of the cell would you expect to be labeled? What would be the consequence of applying TTX to this neuron?
Sodium channels would be labeled. A neuron washed with TTX will have all action potentials blocked.
How does action potential conduction velocity vary with axonal diameter? Why?
If the axon is wide the conduction velocity will be high.
I want some base class members to be accessible to the derived class but not outside the class hierarchy. What access specifier do I use?
protected
If I pass an object of the derived class as an argument to a function that takes a parameter of the base class by value, what happens?
The object is sliced, meaning only the methods of the base class will remain.
Which one should I favor? Private inheritance or composition?
Private inheritance works best for situations in which a derived class only needs 1 instance of the base class.
How does the using keyword help me in an inheritance hierarchy?
It allows access to hidden base class methods.
A class Derived inherits private from class Base. Another class SubDerived inherits public from class Derived. Can SubDerived access public members of class Base?
No. All members of class Base are private to class SubDerived.
When I create an instance of a class using new, where is the class created?
On the free store
My class has a raw pointer int* that contains a dynamically allocated array of integers. Does sizeof report different sizes depending on the number of integers in the dynamic array?
No. The size of the pointer is unaffected.
All my class members are private and my class does not contain any declared friend class or function. Who can access these members?
State the neuroscience doctrine in a single sentence. To whom is this insight credited?
Neurons adhere to cell theory and communicate by contact, not continuity. A histologist and artist from the early 20th century named Cajal.
Which parts of a neuron are shown by a Golgi stain that are not shown by a Nissl stain?
The soma (cell body) and the neurites.
What are three physical characteristics that distinguish axons from dendrites?
Axons are much longer than dendrites.
Dendrites generally taper to a fine point.
There's normally a single axon and multiple dendrites.
Which of the following structures are unique to neurons and which are not? Nucleus, mitochondria, rouch ER, synaptic vesicle, golgi apparatus
Synaptic vesicles are unique to neurons.
Colchicine is a drug that causes microtubules to break apart (deploymerize). What effect would this drug have on anterograde transport? What would happen in the axon terminal?
Without microtubules anterograde transport cannot occur. This will starve the axon and cause Wallerian degeneration.
Classify the cortical pyrimidal cell based on (a) the number of nuerites, (b) the presence or absence of dendritic spines, (c) connections, and (d) axon length.
(a) Multipolar
(b) Spiny
(c) Interneuron
(c) Golgi type 1
What is myelin? What does it do? Which cells provide it in the central nervous system?
An insulating wrap around axons. Speeds the propogation of nerve impulses. Oligodendroglial cells.
What are brain ventricles, and what functions have been ascribed to them over the years?
During the roman empire, a physician named Gulen believed the brain ventricles were used to pump fluid around the body and make it move.
What experiment did Bell Perform to show that the nerves of the body contain a mixture of sensory and motor fibers?
He severed the connection of ventrical roots and dorsal roots, which nerve fibers divide into at the spinal cord, sepparately then observed the loss of muscle control and feeling respectively.
What did flourens' experiements suggest were the functions of the cerebrum and the cerebellum?
The cerebellum plays a role in the coordination of movement. The cerebrum is involved in sensation and perception.
What is the meaning of the term 'animal model'?
Animals/animal tissue used in an experiment.
A region of the cerebrum is now called Broca's area. What function do you think this region performs and why?
Speech production. Broca is famous for studying a man who could understand language but not speak.
What are the different levels of analysis in neuroscience research? What types of question do researchers ask at each level?
Molecular neuroscience
"How do certain molecules give rise to cellular function?"
Cellular neuroscience
"How do neurons perform computations?"
Systems neuroscience
"How do different neural circuits analyze sensory information, form perceptions of the external world, make decisions, and execute movements?"
Behavioral neuroscience
"How do neural systems work together to produce integrated behaviors?"
Cognitive neuroscience
"How do functions of the mind manifest from the brain?"